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Fungal Kti12 proteins display unusual linker regions and unique ATPase p-loops

Kti12 (Kluyveromyces lactis toxin insensitive 12) is an evolutionary highly conserved ATPase, crucial for the tRNA-modification activity of the eukaryotic Elongator complex. The protein consists of an N-terminal ATPase and a C-terminal tRNA-binding domain, which are connected by a flexible linker. T...

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Detalles Bibliográficos
Autores principales: Krutyhołowa, Rościsław, Reinhardt-Tews, Annekathrin, Chramiec-Głąbik, Andrzej, Breunig, Karin D., Glatt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363723/
https://www.ncbi.nlm.nih.gov/pubmed/32236652
http://dx.doi.org/10.1007/s00294-020-01070-2