Evidence for the critical role of the PI3K signaling pathway in particulate matter-induced dysregulation of the inflammatory mediators COX-2/PGE(2) and the associated epithelial barrier protein Filaggrin in the bronchial epithelium

Particulate matter (PM) is an environmental pollutant closely associated with human airway inflammation. However, the molecular mechanisms of PM-related airway inflammation remains to be fully elucidated. It is known that COX-2/PGE(2) play key roles in the pathogenesis of airway inflammation. Filagg...

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Detalles Bibliográficos
Autores principales: Song, Chenjian, Liu, Lingjing, Chen, Junjie, Hu, Yiran, Li, Jingli, Wang, Beibei, Bellusci, Saverio, Chen, Chengshui, Dong, Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363729/
https://www.ncbi.nlm.nih.gov/pubmed/31884678
http://dx.doi.org/10.1007/s10565-019-09508-1

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