Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation

Phenotypes of haploid embryonic stem cells (haESCs) are dominant for recessive traits in mice. However, one major obstacle to their use is self-diploidization in daily culture. Although haESCs maintain haploidy well by deleting p53, whether they can sustain haploidy in differentiated status and the...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhao, Tian, Yaru, Gao, Qian, Li, Xu, Li, Yanni, Zhang, Jinxin, Yao, Chunmeng, Wang, Yuna, Wang, Haoyu, Zhao, Yiding, Zhang, Qian, Li, Luyuan, Yu, Yang, Fan, Yong, Shuai, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363743/
https://www.ncbi.nlm.nih.gov/pubmed/32502463
http://dx.doi.org/10.1016/j.stemcr.2020.05.004

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