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Hedgehog Activation Regulates Human Osteoblastogenesis

Two genetic diseases, Gorlin syndrome and McCune-Albright syndrome (MAS), show completely opposite symptoms in terms of bone mineral density and hedgehog (Hh) activity. In this study, we utilized human induced pluripotent stem cell (iPSC)-based models of the two diseases to understand the roles of H...

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Detalles Bibliográficos
Autores principales: Onodera, Shoko, Saito, Akiko, Hojo, Hironori, Nakamura, Takashi, Zujur, Denise, Watanabe, Katsuhito, Morita, Nana, Hasegawa, Daigo, Masaki, Hideki, Nakauchi, Hiromitsu, Nomura, Takeshi, Shibahara, Takahiko, Yamaguchi, Akira, Chung, Ung-il, Azuma, Toshifumi, Ohba, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363748/
https://www.ncbi.nlm.nih.gov/pubmed/32531191
http://dx.doi.org/10.1016/j.stemcr.2020.05.008