Cargando…
Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by interstitial remodeling and pulmonary dysfunction. The etiology of IPF is not completely understood but involves pathologic inflammation and subsequent failure to resolve fibrosis in response to epithelial injury. Treatmen...
Autores principales: | Smith, Julianne N. P., Witkin, Matthew D., Jogasuria, Alvin P., Christo, Kelsey F., Raffay, Thomas M., Markowitz, Sanford D., Desai, Amar B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363833/ https://www.ncbi.nlm.nih.gov/pubmed/32669620 http://dx.doi.org/10.1038/s41598-020-68336-0 |
Ejemplares similares
-
15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration
por: Smith, Julianne N.P., et al.
Publicado: (2021) -
15-PGDH regulates hematopoietic and gastrointestinal fitness during aging
por: Ho, Won Jin, et al.
Publicado: (2022) -
Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291
por: Dogan, Alan B., et al.
Publicado: (2021) -
Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system
por: Huang, Wei, et al.
Publicado: (2023) -
A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support
por: Desai, Amar, et al.
Publicado: (2018)