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ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment

Advanced ovarian cancer usually spreads to the omentum. However, the omental cell-derived molecular determinants modulating its progression have not been thoroughly characterized. Here, we show that circulating ITLN1 has prognostic significance in patients with advanced ovarian cancer. Further studi...

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Detalles Bibliográficos
Autores principales: Au-Yeung, Chi-Lam, Yeung, Tsz-Lun, Achreja, Abhinav, Zhao, Hongyun, Yip, Kay-Pong, Kwan, Suet-Ying, Onstad, Michaela, Sheng, Jianting, Zhu, Ying, Baluya, Dodge L., Co, Ngai-Na, Rynne-Vidal, Angela, Schmandt, Rosemarie, Anderson, Matthew L., Lu, Karen H., Wong, Stephen T. C., Nagrath, Deepak, Mok, Samuel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363861/
https://www.ncbi.nlm.nih.gov/pubmed/32669559
http://dx.doi.org/10.1038/s41467-020-17383-2