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Transplantation of Skin Precursor-Derived Schwann Cells Yields Better Locomotor Outcomes and Reduces Bladder Pathology in Rats with Chronic Spinal Cord Injury

Cell transplantation for spinal cord injury (SCI) has largely been studied in sub-acute settings within 1–2 weeks of injury. In contrast, here we transplanted skin-derived precursors differentiated into Schwann cells (SKP-SCs) into the contused rat spinal cord 8 weeks post-injury (wpi). Twenty-one w...

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Detalles Bibliográficos
Autores principales: Assinck, Peggy, Sparling, Joseph S., Dworski, Shaalee, Duncan, Greg J., Wu, Di L., Liu, Jie, Kwon, Brian K., Biernaskie, Jeff, Miller, Freda D., Tetzlaff, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363874/
https://www.ncbi.nlm.nih.gov/pubmed/32559459
http://dx.doi.org/10.1016/j.stemcr.2020.05.017