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Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids

Retinal ganglion cells (RGCs) serve as the connection between the eye and the brain, with this connection disrupted in glaucoma. Numerous cellular mechanisms have been associated with glaucomatous neurodegeneration, and useful cellular models of glaucoma allow for the precise analysis of degenerativ...

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Detalles Bibliográficos
Autores principales:	VanderWall, Kirstin B., Huang, Kang-Chieh, Pan, Yanling, Lavekar, Sailee S., Fligor, Clarisse M., Allsop, Anna R., Lentsch, Kelly A., Dang, Pengtao, Zhang, Chi, Tseng, Henry C., Cummins, Theodore R., Meyer, Jason S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363877/ https://www.ncbi.nlm.nih.gov/pubmed/32531194 http://dx.doi.org/10.1016/j.stemcr.2020.05.009

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