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Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition

Intestinal crypts have great capacity for repair and regeneration after intestinal stem cell (ISC) injury. Here, we define the cellular remodeling process resulting from ISC niche interruption by transient Notch pathway inhibition in adult mice. Although ISCs were retained, lineage tracing demonstra...

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Detalles Bibliográficos
Autores principales:	Bohin, Natacha, Keeley, Theresa M., Carulli, Alexis J., Walker, Emily M., Carlson, Elizabeth A., Gao, Jie, Aifantis, Iannis, Siebel, Christian W., Rajala, Michael W., Myers, Martin G., Jones, Jennifer C., Brindley, Constance D., Dempsey, Peter J., Samuelson, Linda C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363878/ https://www.ncbi.nlm.nih.gov/pubmed/32531190 http://dx.doi.org/10.1016/j.stemcr.2020.05.010

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