In Vitro Differentiated Human Stem Cell-Derived Neurons Reproduce Synaptic Synchronicity Arising during Neurodevelopment

Neurons differentiated from induced pluripotent stem cells (iPSCs) typically show regular spiking and synaptic activity but lack more complex network activity critical for brain development, such as periodic depolarizations including simultaneous involvement of glutamatergic and GABAergic neurotrans...

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Detalles Bibliográficos
Autores principales: Rosa, Filip, Dhingra, Ashutosh, Uysal, Betül, Mendis, G. Dulini C., Loeffler, Heidi, Elsen, Gina, Mueller, Stephan, Schwarz, Niklas, Castillo-Lizardo, Melissa, Cuddy, Claire, Becker, Felicitas, Heutink, Peter, Reid, Christopher A., Petrou, Steven, Lerche, Holger, Maljevic, Snezana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363884/
https://www.ncbi.nlm.nih.gov/pubmed/32559460
http://dx.doi.org/10.1016/j.stemcr.2020.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363884/
https://www.ncbi.nlm.nih.gov/pubmed/32559460
http://dx.doi.org/10.1016/j.stemcr.2020.05.015

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