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Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells

More than 94% of colorectal cancer cases have mutations in one or more Wnt/β-catenin signaling pathway components. Inactivating mutations in APC or activating mutations in β-catenin (CTNNB1) lead to signaling overactivation and subsequent intestinal hyperplasia. Numerous classes of medicines derived...

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Detalles Bibliográficos
Autores principales:	de Almeida, Gracielle C., Oliveira, Luiz F. S., Predes, Danilo, Fokoue, Harold H., Kuster, Ricardo M., Oliveira, Felipe L., Mendes, Fabio A., Abreu, Jose G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363889/ https://www.ncbi.nlm.nih.gov/pubmed/32669593 http://dx.doi.org/10.1038/s41598-020-68574-2

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