Cargando…

Targeting the Microenvironment in MDS: The Final Frontier

Myelodysplastic syndromes (MDS) are a heterogeneous group of malignant disorders of hematopoietic stem and progenitor cells (HSPC), mainly characterized by ineffective hematopoiesis leading to peripheral cytopenias and progressive bone marrow failure. While clonal dominance is nearly universal at di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teodorescu, Patric, Pasca, Sergiu, Dima, Delia, Tomuleasa, Ciprian, Ghiaur, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364152/ https://www.ncbi.nlm.nih.gov/pubmed/32742264 http://dx.doi.org/10.3389/fphar.2020.01044

Ejemplares similares

KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma
por: Pasca, Sergiu, et al.
Publicado: (2019)

Editorial: Novel Drugs Targeting the Microenvironment and the Epigenetic Changes in Hematopoietic Malignancies
por: Gulei, Diana, et al.
Publicado: (2020)

The Coming of Age of Preclinical Models of MDS
por: Liu, Wei, et al.
Publicado: (2022)

Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology
por: Moisoiu, Vlad, et al.
Publicado: (2019)

The Predictive Role of Modified Early Warning Score in 174 Hematological Patients at the Point of Transfer to the Intensive Care Unit
por: Constantinescu, Catalin, et al.
Publicado: (2021)

Clinical Approach to the Patient in Critical State Following Immunotherapy and/or Stem Cell Transplantation: Guideline for the On-Call Physician
por: Constantinescu, Catalin, et al.
Publicado: (2019)

Correlation between the prevalence of T-cell lymphomas and alcohol consumption
por: Desmirean, Minodora, et al.
Publicado: (2021)

Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies?
por: Constantinescu, Catalin, et al.
Publicado: (2020)

B Cells versus T Cells in the Tumor Microenvironment of Malignant Lymphomas. Are the Lymphocytes Playing the Roles of Muhammad Ali versus George Foreman in Zaire 1974?
por: Desmirean, Minodora, et al.
Publicado: (2020)

Persistent Basophilia May Suggest an “Accelerated Phase” in the Evolution of CALR-Positive Primary Myelofibrosis Toward Acute Myeloid Leukemia
por: Dobrowolski, Jerome, et al.
Publicado: (2019)

Overview of the Side-Effects of FDA- and/or EMA-Approved Targeted Therapies for the Treatment of Hematological Malignancies
por: Constantinescu, Catalin, et al.
Publicado: (2020)

Coagulopathy in Acute Promyelocytic Leukemia: Can We Go Beyond Supportive Care?
por: Hambley, Bryan C., et al.
Publicado: (2021)

Transforming growth factor β‐mediated micromechanics modulates disease progression in primary myelofibrosis
por: Teodorescu, Patric, et al.
Publicado: (2020)

TET2/IDH1/2/WT1 and NPM1 Mutations Influence the RUNX1 Expression Correlations in Acute Myeloid Leukemia
por: Pasca, Sergiu, et al.
Publicado: (2020)

The Potential Equivalents of TET2 Mutations
por: Pasca, Sergiu, et al.
Publicado: (2021)

Haematology patients infected with SARS-CoV-2, pretreated with eculizumab or siltuximab, develop oligosymptomatic disease
por: Iluta, Sabina, et al.
Publicado: (2022)

The use of rotation to fentanyl in cancer-related pain
por: Dima, Delia, et al.
Publicado: (2017)

The Influence of Methylating Mutations on Acute Myeloid Leukemia: Preliminary Analysis on 56 Patients
por: Pasca, Sergiu, et al.
Publicado: (2020)

Azacytidine plus olaparib for relapsed acute myeloid leukaemia, ineligible for intensive chemotherapy, diagnosed with a synchronous malignancy
por: Iluta, Sabina, et al.
Publicado: (2021)

Differential Diagnosis of Malignant Lymphadenopathy Using Flow Cytometry on Fine Needle Aspirate: Report on 269 Cases
por: Griesel, Carla, et al.
Publicado: (2020)

Topical Corticosteroids a Viable Solution for Oral Graft versus Host Disease? A Systematic Insight on Randomized Clinical Trials
por: Sava, Arin, et al.
Publicado: (2020)

MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases
por: Pasca, Sergiu, et al.
Publicado: (2020)

Medical Application of Hydrogen in Hematological Diseases
por: Qian, Liren, et al.
Publicado: (2019)

SERS-Based Assessment of MRD in Acute Promyelocytic Leukemia?
por: Turcas, Cristina, et al.
Publicado: (2020)

LEAM vs. BEAM vs. CLV Conditioning Regimen for Autologous Stem Cell Transplantation in Malignant Lymphomas. Retrospective Comparison of Toxicity and Efficacy on 222 Patients in the First 100 Days After Transplant, On Behalf of the Romanian Society for Bone Marrow Transplantation
por: Colita, Andrei, et al.
Publicado: (2019)

SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome
por: Moisoiu, Vlad, et al.
Publicado: (2021)

Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia
por: Tomuleasa, Ciprian, et al.
Publicado: (2018)

Let’s Talk About BiTEs and Other Drugs in the Real-Life Setting for B-Cell Acute Lymphoblastic Leukemia
por: Deak, Dalma, et al.
Publicado: (2019)

Hotspots and Frontiers in Inflammatory Tumor Microenvironment Research: A Scientometric and Visualization Analysis
por: Zhang, Yuli, et al.
Publicado: (2022)

Genetically enhanced T lymphocytes and the intensive care unit
por: Tat, Tiberiu, et al.
Publicado: (2018)

Correction: Genetically enhanced T lymphocytes and the intensive care unit
por: Tat, Tiberiu, et al.
Publicado: (2018)

Current therapeutic approaches in the management of hemophilia—a consensus view by the Romanian Society of Hematology
por: Hotea, Ionut, et al.
Publicado: (2021)

Characteristics of Dental Resin-Based Composites in Leukemia Saliva: An In Vitro Analysis
por: Mester, Alexandru, et al.
Publicado: (2021)

The Final Frontier
por: Purvis, John
Publicado: (2020)

The final frontier
por: Randall, Lisa
Publicado: (2005)

The final frontier
por: Horgan, John
Publicado: (2006)

Design and preclinical testing of an anti‐CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia
por: Tigu, Adrian Bogdan, et al.
Publicado: (2023)

Ibrutinib Monotherapy as Bridge-to-Transplant for Relapsed/Refractory Primary Oculo-Cerebral Lymphoma
por: Deak-Mihaly, Dalma, et al.
Publicado: (2021)

Metabolomics: the final frontier?
por: Veenstra, Timothy D
Publicado: (2012)

Fabric of the final frontier
por: Russell, N
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_8m2hp9bm278hb23mc8khh6j1j9