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Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HBV Replication through Production of IFN-γ and TNF-⍺

The viral antigen (Ag)-specific CD8(+) cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress hepatitis B virus (HBV) infection. After adoptive transfer, PSC-CTLs can infiltrate into the liver to suppress HBV replication. Nevertheless,...

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Detalles Bibliográficos
Autores principales:	Haque, Mohammad, Lei, Fengyang, Xiong, Xiaofang, Ren, Yijie, Kumar, Anil, Das, Jugal Kishore, Ren, Xingcong, Fang, Deyu, de Figueiredo, Paul, Yang, Jin-Ming, Song, Jianxun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364173/ https://www.ncbi.nlm.nih.gov/pubmed/32679546 http://dx.doi.org/10.1016/j.isci.2020.101333

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