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Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss

BACKGROUND AND OBJECTIVES: In this study, we compared the outcomes of patients with idiopathic sudden sensorineural hearing loss who underwent steroid treatment with or without hyperbaric oxygen (HBO) therapy and were followed-up in our clinic. SUBJECTS AND METHODS: Patients were divided into two gr...

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Autores principales: Yücel, Abitter, Özbuğday, Yaşar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Audiological Society and Korean Otological Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364192/
https://www.ncbi.nlm.nih.gov/pubmed/32397013
http://dx.doi.org/10.7874/jao.2019.00486
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author Yücel, Abitter
Özbuğday, Yaşar
author_facet Yücel, Abitter
Özbuğday, Yaşar
author_sort Yücel, Abitter
collection PubMed
description BACKGROUND AND OBJECTIVES: In this study, we compared the outcomes of patients with idiopathic sudden sensorineural hearing loss who underwent steroid treatment with or without hyperbaric oxygen (HBO) therapy and were followed-up in our clinic. SUBJECTS AND METHODS: Patients were divided into two groups according to their treatment regimen. Steroid group received intravenous 1 mg/kg methylprednisolone which was due to be completed in 2-3 weeks with decreasing doses, and five doses of 0.5 mL intratympanic dexamethasone. Steroid+HBO group received the same steroid treatment with the addition of HBO therapy. The audiologic results of both treatment groups were compared after considering the patients’ risk factors. RESULTS: There was no significant difference between the steroid and Steroid+HBO groups in terms of hearing gain and degree of recovery, both at all degrees of hearing loss, and in severe and profound hearing loss. Hearing gain was similar when evaluated by audiogram type and admission time in both treatment groups. CONCLUSIONS: We found that the addition of HBO therapy to systemic plus intratympanic steroid treatment did not affect hearing gain at all degrees of hearing loss in this study. Furthermore, audiogram type and admission time did not affect hearing gain between the two groups.
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spelling pubmed-73641922020-07-24 Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss Yücel, Abitter Özbuğday, Yaşar J Audiol Otol Original Article BACKGROUND AND OBJECTIVES: In this study, we compared the outcomes of patients with idiopathic sudden sensorineural hearing loss who underwent steroid treatment with or without hyperbaric oxygen (HBO) therapy and were followed-up in our clinic. SUBJECTS AND METHODS: Patients were divided into two groups according to their treatment regimen. Steroid group received intravenous 1 mg/kg methylprednisolone which was due to be completed in 2-3 weeks with decreasing doses, and five doses of 0.5 mL intratympanic dexamethasone. Steroid+HBO group received the same steroid treatment with the addition of HBO therapy. The audiologic results of both treatment groups were compared after considering the patients’ risk factors. RESULTS: There was no significant difference between the steroid and Steroid+HBO groups in terms of hearing gain and degree of recovery, both at all degrees of hearing loss, and in severe and profound hearing loss. Hearing gain was similar when evaluated by audiogram type and admission time in both treatment groups. CONCLUSIONS: We found that the addition of HBO therapy to systemic plus intratympanic steroid treatment did not affect hearing gain at all degrees of hearing loss in this study. Furthermore, audiogram type and admission time did not affect hearing gain between the two groups. The Korean Audiological Society and Korean Otological Society 2020-07 2020-05-14 /pmc/articles/PMC7364192/ /pubmed/32397013 http://dx.doi.org/10.7874/jao.2019.00486 Text en Copyright © 2020 The Korean Audiological Society and Korean Otological Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yücel, Abitter
Özbuğday, Yaşar
Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title_full Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title_fullStr Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title_full_unstemmed Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title_short Comparison of Steroid Treatment with and without Hyperbaric Oxygen Therapy for Idiopathic Sudden Sensorineural Hearing Loss
title_sort comparison of steroid treatment with and without hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364192/
https://www.ncbi.nlm.nih.gov/pubmed/32397013
http://dx.doi.org/10.7874/jao.2019.00486
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