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DNA Methylation Epigenetically Regulates Gene Expression in Burkholderia cenocepacia and Controls Biofilm Formation, Cell Aggregation, and Motility

Respiratory tract infections by the opportunistic pathogen Burkholderia cenocepacia often lead to severe lung damage in cystic fibrosis (CF) patients. New insights in how to tackle these infections might emerge from the field of epigenetics, as DNA methylation is an important regulator of gene expre...

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Detalles Bibliográficos
Autores principales: Vandenbussche, Ian, Sass, Andrea, Pinto-Carbó, Marta, Mannweiler, Olga, Eberl, Leo, Coenye, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364216/
https://www.ncbi.nlm.nih.gov/pubmed/32669472
http://dx.doi.org/10.1128/mSphere.00455-20