An Important Role for CD4(+) T Cells in Adaptive Immunity to Toxoplasma gondii in Mice Lacking the Transcription Factor Batf3

Immunity to Toxoplasma gondii at early stages of infection in C57BL/6 mice depends on gamma interferon (IFN-γ) production by NK cells, while at later stages it is primarily mediated by CD8 T cells. We decided to explore the requirement for CD4 T cells during T. gondii infection in Batf3(−/−) mice, w...

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Detalles Bibliográficos
Autores principales: Tussiwand, Roxane, Behnke, Michael S., Kretzer, Nicole M., Grajales-Reyes, Gary E., Murphy, Theresa L., Schreiber, Robert D., Murphy, Kenneth M., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364223/
https://www.ncbi.nlm.nih.gov/pubmed/32669460
http://dx.doi.org/10.1128/mSphere.00634-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364223/
https://www.ncbi.nlm.nih.gov/pubmed/32669460
http://dx.doi.org/10.1128/mSphere.00634-20

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