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Advances in Exosomes Derived from Different Cell Sources and Cardiovascular Diseases

Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mec...

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Detalles Bibliográficos
Autores principales: Liang, Bo, He, Xin, Zhao, Yu-Xiu, Zhang, Xiao-Xiao, Gu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364237/
https://www.ncbi.nlm.nih.gov/pubmed/32724810
http://dx.doi.org/10.1155/2020/7298687
Descripción
Sumario:Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. In addition to being biomarkers, exosomes also have a certain significance in the diagnosis, treatment, and even prevention of cardiovascular diseases. Here, we provide a review of the up-to-date applications of exosomes, derived from various sources, in the prognosis and diagnosis of cardiovascular diseases.