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Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia

We herein report a 24-year-old male construction worker with occupational lead poisoning who presented with acute abdomen and normocytic anemia. The levels of urinary delta-aminolevulinic acid and free erythrocyte protoporphyrin were elevated without any increase in the level of urine porphobilinoge...

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Autores principales: Kaneko, Masahiko, Kazatani, Takurou, Shikata, Hisaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364248/
https://www.ncbi.nlm.nih.gov/pubmed/32536679
http://dx.doi.org/10.2169/internalmedicine.4176-19
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author Kaneko, Masahiko
Kazatani, Takurou
Shikata, Hisaharu
author_facet Kaneko, Masahiko
Kazatani, Takurou
Shikata, Hisaharu
author_sort Kaneko, Masahiko
collection PubMed
description We herein report a 24-year-old male construction worker with occupational lead poisoning who presented with acute abdomen and normocytic anemia. The levels of urinary delta-aminolevulinic acid and free erythrocyte protoporphyrin were elevated without any increase in the level of urine porphobilinogen. Detection of an elevated blood lead level of 100 μg/dL confirmed a diagnosis of lead poisoning. Chelation therapy with calcium disodium ethylenediaminetetraacetate resulted in prompt improvement of the clinical symptoms and the blood lead level. Clinicians should be aware that lead poisoning caused by occupational exposure can still occur sporadically in construction workers in Japan.
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spelling pubmed-73642482020-07-30 Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia Kaneko, Masahiko Kazatani, Takurou Shikata, Hisaharu Intern Med Case Report We herein report a 24-year-old male construction worker with occupational lead poisoning who presented with acute abdomen and normocytic anemia. The levels of urinary delta-aminolevulinic acid and free erythrocyte protoporphyrin were elevated without any increase in the level of urine porphobilinogen. Detection of an elevated blood lead level of 100 μg/dL confirmed a diagnosis of lead poisoning. Chelation therapy with calcium disodium ethylenediaminetetraacetate resulted in prompt improvement of the clinical symptoms and the blood lead level. Clinicians should be aware that lead poisoning caused by occupational exposure can still occur sporadically in construction workers in Japan. The Japanese Society of Internal Medicine 2020-06-15 2020-06-15 /pmc/articles/PMC7364248/ /pubmed/32536679 http://dx.doi.org/10.2169/internalmedicine.4176-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kaneko, Masahiko
Kazatani, Takurou
Shikata, Hisaharu
Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title_full Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title_fullStr Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title_full_unstemmed Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title_short Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia
title_sort occupational lead poisoning in a patient with acute abdomen and normocytic anemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364248/
https://www.ncbi.nlm.nih.gov/pubmed/32536679
http://dx.doi.org/10.2169/internalmedicine.4176-19
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