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Guidelines To Predict Binding Poses of Antibody–Integrin Complexes

[Image: see text] Integrins are cell adhesion receptors that transmit bidirectional signals across the plasma membrane. They are noncovalently linked heterodimeric molecules consisting of two subunits and act as biomarkers in several pathologies. Thus, according to the increase of therapeutic antibo...

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Detalles Bibliográficos
Autores principales: Chaves, Beatriz, Sartori, Geraldo R., Vasconcelos, Disraeli C. A., Savino, Wilson, Caffarena, Ernesto R., Cotta-de-Almeida, Vinícius, da Silva, João H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364430/
https://www.ncbi.nlm.nih.gov/pubmed/32685800
http://dx.doi.org/10.1021/acsomega.0c00226