Cargando…

Single-molecule analysis of subtelomeres and telomeres in Alternative Lengthening of Telomeres (ALT) cells

BACKGROUND: Telomeric DNA is typically comprised of G-rich tandem repeat motifs and maintained by telomerase (Greider CW, Blackburn EH; Cell 51:887–898; 1987). In eukaryotes lacking telomerase, a variety of DNA repair and DNA recombination based pathways for telomere maintenance have evolved in orga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abid, Heba Z., McCaffrey, Jennifer, Raseley, Kaitlin, Young, Eleanor, Lassahn, Katy, Varapula, Dharma, Riethman, Harold, Xiao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364475/ https://www.ncbi.nlm.nih.gov/pubmed/32669102 http://dx.doi.org/10.1186/s12864-020-06901-7

Ejemplares similares

High-throughput single-molecule telomere characterization
por: McCaffrey, Jennifer, et al.
Publicado: (2017)

Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway
por: Toubiana, Shir, et al.
Publicado: (2021)

High-throughput single-molecule mapping links subtelomeric variants and long-range haplotypes with specific telomeres
por: Young, Eleanor, et al.
Publicado: (2017)

The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
por: Amorim, João P., et al.
Publicado: (2016)

Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT)
por: De Vitis, Marco, et al.
Publicado: (2018)

Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
por: Rosso, Ilaria, et al.
Publicado: (2023)

Alternative lengthening of telomeres (ALT) in cancer stem cells in vivo
por: Bojovic, Bojana, et al.
Publicado: (2014)

Alternative Lengthening of Telomeres (ALT) in Tumors and Pluripotent Stem Cells
por: Zhao, Shuang, et al.
Publicado: (2019)

The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT)
por: Sohn, Eric J., et al.
Publicado: (2023)

Customized optical mapping by CRISPR–Cas9 mediated DNA labeling with multiple sgRNAs
por: Abid, Heba Z, et al.
Publicado: (2020)

Single-Molecule Telomere Assay via Optical Mapping (SMTA-OM) Can Potentially Define the ALT Positivity of Cancer
por: Raseley, Kaitlin, et al.
Publicado: (2023)

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
por: Kusuma, Frances Karla, et al.
Publicado: (2023)

MEDB-68. Analysis of telomeres length and Alternative Lengthening of Telomeres (ALT) in molecular subgroups of infant medulloblastoma
por: Buttarelli, Francesca Romana, et al.
Publicado: (2022)

ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres
por: O’Rourke, Julienne J, et al.
Publicado: (2019)

Alternative lengthening of telomeres: remodeling the telomere architecture
por: Conomos, Dimitri, et al.
Publicado: (2013)

Alternative Lengthening of Telomeres and Mediated Telomere Synthesis
por: Hou, Kailong, et al.
Publicado: (2022)

TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes
por: Armendáriz-Castillo, Isaac, et al.
Publicado: (2020)

ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats
por: Frank, Lukas, et al.
Publicado: (2022)

Potential clinical treatment prospects behind the molecular mechanism of alternative lengthening of telomeres (ALT)
por: Sun, Haolu, et al.
Publicado: (2023)

Comprehensive Analysis of Human Subtelomeres by Whole Genome Mapping
por: Young, Eleanor, et al.
Publicado: (2020)

Detection of alternative lengthening of telomeres by telomere quantitative PCR
por: Lau, Loretta M. S., et al.
Publicado: (2013)

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
por: Lu, Robert, et al.
Publicado: (2019)

Alternative Lengthening of Telomeres (ALT) in Pancreatic Neuroendocrine Tumors: Ready for Prime-Time in Clinical Practice?
por: Luchini, Claudio, et al.
Publicado: (2021)

Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin
por: Episkopou, Harikleia, et al.
Publicado: (2014)

ATRX represses alternative lengthening of telomeres
por: Napier, Christine E., et al.
Publicado: (2015)

Alternative Lengthening of Telomeres and Chromatin Status
por: Udroiu, Ion, et al.
Publicado: (2019)

Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers
por: Lu, Robert, et al.
Publicado: (2022)

The alternative lengthening of telomeres mechanism jeopardizes telomere integrity if not properly restricted
por: Silva, Bruno, et al.
Publicado: (2022)

Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis
por: Lawlor, Rita T., et al.
Publicado: (2019)

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
por: Lu, Robert, et al.
Publicado: (2019)

G-quadruplexes mark alternative lengthening of telomeres
por: Yang, Sunny Y, et al.
Publicado: (2021)

ATR Inhibition Broadly Sensitizes Soft-Tissue Sarcoma Cells to Chemotherapy Independent of Alternative Lengthening Telomere (ALT) Status
por: Laroche-Clary, Audrey, et al.
Publicado: (2020)

A micropatterned substrate for on-surface enzymatic labelling of linearized long DNA molecules
por: Varapula, Dharma, et al.
Publicado: (2019)

Telomere clustering drives ALT
por: Min, Jaewon, et al.
Publicado: (2019)

Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity
por: Sung, Ji-Yong, et al.
Publicado: (2020)

Alternative Lengthening of Telomeres in the Budding Yeast Naumovozyma castellii
por: Cohn, Marita, et al.
Publicado: (2019)

Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies
por: Kent, Thomas, et al.
Publicado: (2020)

Alternative lengthening of telomeres is not synonymous with mutations in ATRX/DAXX
por: de Nonneville, Alexandre, et al.
Publicado: (2021)

Detection of alternative lengthening of telomeres mechanism on tumor sections
por: Claude, Eloïse, et al.
Publicado: (2021)

Alternative Lengthening of Telomeres Is Rare in Canine Histiocytic Sarcoma
por: Kreilmeier-Berger, Theresa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0ek0m1e6v02p62mg3kckp85ji3