Cargando…

Validation of the T86I mutation in the gyrA gene as a highly reliable real time PCR target to detect Fluoroquinolone-resistant Campylobacter jejuni

BACKGROUND: Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and increasing rates of fluoroquinolone (FQ) resistance in C. jejuni are a major public health concern. The rapid detection and tracking of FQ resistance are critical needs in developing countries, as these antimicr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Espinoza, Nereyda, Rojas, Jesús, Pollett, Simon, Meza, Rina, Patiño, Lilian, Leiva, Manuel, Camiña, Máximo, Bernal, Manuela, Reynolds, Nathanael D., Maves, Ryan, Tilley, Drake H., Kasper, Matthew, Simons, Mark P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364496/ https://www.ncbi.nlm.nih.gov/pubmed/32677920 http://dx.doi.org/10.1186/s12879-020-05202-4

Ejemplares similares

A Fluoroquinolone Resistance Associated Mutation in gyrA Affects DNA Supercoiling in Campylobacter jejuni
por: Han, Jing, et al.
Publicado: (2012)

Droplet Digital PCR-Based Detection and Quantification of GyrA Thr-86-Ile Mutation Based Fluoroquinolone-Resistant Campylobacter jejuni
por: Luo, Yi, et al.
Publicado: (2022)

gyrA Mutations in Fluoroquinolone-resistant Clostridium difficile PCR-027
por: Drudy, Denise, et al.
Publicado: (2007)

Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patients
por: Kabir, Saba, et al.
Publicado: (2020)

New Insights into Fluoroquinolone Resistance in Mycobacterium tuberculosis: Functional Genetic Analysis of gyrA and gyrB Mutations
por: Malik, Seidu, et al.
Publicado: (2012)

Alterations of gyrA, gyrB, and parC and Activity of Efflux Pump in Fluoroquinolone-resistant Acinetobacter baumannii
por: Park, Sunok, et al.
Publicado: (2011)

Fluoroquinolone Resistance Linked to GyrA, GyrB, and ParC Mutations in Salmonella enterica Typhimurium Isolates in Humans
por: Casin, Isabelle, et al.
Publicado: (2003)

1495 Resistance of Fluoroquinolone in Orientia tsutsugamushi Due to gyrA Mutation in Scrub typhus
por: CHO, Soo Kyung, et al.
Publicado: (2014)

Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis
por: Li, Jing, et al.
Publicado: (2014)

gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya
por: Kivata, Mary Wandia, et al.
Publicado: (2019)

Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis
por: Anand, RS, et al.
Publicado: (2011)

Mutations in gyrA & parC genes of Shigella flexneri 2a determining the fluoroquinolone resistance
por: Divya, M.P., et al.
Publicado: (2015)

The role of gyrA and parC mutations in fluoroquinolones-resistant Pseudomonas aeruginosa isolates from Iran
por: Nouri, Roghayeh, et al.
Publicado: (2016)

Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis Isolates: A Systematic Review
por: Avalos, Elisea, et al.
Publicado: (2015)

Hotspots sequences of gyrA, gyrB, parC, and parE genes encoded for fluoroquinolones resistance from local Salmonella Typhi strains in Jakarta
por: Nathania, Ignes, et al.
Publicado: (2022)

Resistance Mutations in gyrA and parC are Common in Escherichia Communities of both Fluoroquinolone-Polluted and Uncontaminated Aquatic Environments
por: Johnning, Anna, et al.
Publicado: (2015)

Profiles of gyrA Mutations and Plasmid-Mediated Quinolone Resistance Genes in Shigella Isolates with Different Levels of Fluoroquinolone Susceptibility
por: Yu, Xuxia, et al.
Publicado: (2020)

Characterization of DNA Gyrase Activity and Elucidation of the Impact of Amino Acid Substitution in GyrA on Fluoroquinolone Resistance in Mycobacterium avium
por: Thapa, Jeewan, et al.
Publicado: (2023)

Campylobacter antimicrobial resistance in Peru: a ten-year observational study
por: Pollett, Simon, et al.
Publicado: (2012)

Life-Threatening Infantile Diarrhea from Fluoroquinolone-Resistant Salmonella enteric Typhimurium with Mutations in Both gyrA and parC
por: Nakaya, Hideo, et al.
Publicado: (2003)

Design and virtual screening of novel fluoroquinolone analogs as effective mutant DNA GyrA inhibitors against urinary tract infection-causing fluoroquinolone resistant Escherichia coli
por: Balasubramaniyan, Sakthivel, et al.
Publicado: (2018)

First report of molecular detection of fluoroquinolone resistance-associated gyrA mutations in multidrug-resistant clinical Mycobacterium tuberculosis isolates in Kuwait
por: Al-Mutairi, Noura M, et al.
Publicado: (2011)

Mutations in the gyrA, parC, and mexR genes provide functional insights into the fluoroquinolone-resistant Pseudomonas aeruginosa isolated in Vietnam
por: Nguyen, Kinh Van, et al.
Publicado: (2018)

Prevalence of fluoroquinolone resistance and mutations in the gyrA, parC and parE genes of Riemerella anatipestifer isolated from ducks in China
por: Zhu, Dekang, et al.
Publicado: (2019)

Study of Mutations in the DNA gyrase gyrA Gene of Escherichia coli
por: Pourahmad Jaktaji, Razieh, et al.
Publicado: (2010)

Investigating the Roles of the C-Terminal Domain of Plasmodium falciparum GyrA
por: Nagano, Soshichiro, et al.
Publicado: (2015)

An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins
por: Marshall, Carrie J., et al.
Publicado: (2014)

Molecular Evolution of the Pseudomonas aeruginosa DNA Gyrase gyrA Gene
por: Sada, Mitsuru, et al.
Publicado: (2022)

Molecular Detection of gyrA Mutation in Clinical Strains of Klebsiella pneumoniae
por: Ahmadi, Zeinab, et al.
Publicado: (2022)

First Report of aac(6′)-Ib and aac(6′)-Ib-cr Variant Genes Associated with Mutations in gyrA Encoded Fluoroquinolone Resistance in Avian Campylobacter coli Strains Collected in Tunisia
por: Gharbi, Manel, et al.
Publicado: (2023)

Emergence of Fluoroquinolone-Resistant Campylobacter jejuni and Campylobacter coli among Australian Chickens in the Absence of Fluoroquinolone Use
por: Abraham, Sam, et al.
Publicado: (2020)

Interaction between rpsL and gyrA mutations affects the fitness and dual resistance of Mycobacterium tuberculosis clinical isolates against streptomycin and fluoroquinolones
por: Sun, Honghu, et al.
Publicado: (2018)

Molecular Study of Quinolone Resistance Determining Regions of gyrA Gene and parC Genes in Clinical Isolates of Acintobacter baumannii Resistant to Fluoroquinolone
por: Zaki, Maysaa El Sayed, et al.
Publicado: (2018)

Ciprofloxacin binding to GyrA causes global changes in the proteome of Pseudomonas aeruginosa
por: Jedrey, Hannah, et al.
Publicado: (2018)

Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli
por: Dages, Samantha, et al.
Publicado: (2018)

gyrA ser83 mutation among fluoroquinolone-resistant Salmonella enterica serovars from enteric fever patients in tertiary care hospital, Kathmandu
por: Adhikari, Prashanna, et al.
Publicado: (2022)

Key Role of Mfd in the Development of Fluoroquinolone Resistance in Campylobacter jejuni
por: Han, Jing, et al.
Publicado: (2008)

Distribution of CRISPR Types in Fluoroquinolone-Resistant Campylobacter jejuni Isolates
por: Adiguzel, Mehmet Cemal, et al.
Publicado: (2021)

Development of Fluoroquinolone Resistance through Antibiotic Tolerance in Campylobacter jejuni
por: Park, Myungseo, et al.
Publicado: (2022)

Distribution of Capsular Types of Campylobacter jejuni Isolates from Symptomatic and Asymptomatic Children in Peru
por: Rojas, Jesús D., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_si8n1ifqs3cq86ker09rdlhalj