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IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction

BACKGROUND: IGF1 is a key molecule in the regulation of growth and metabolism. Low IGF1 secretion is known to cause growth restriction in childhood, as well as deregulated lipid metabolism, cardiovascular disease, and diabetes in adulthood. The IGF1 gene P2 promoter is highly methylated, resulting i...

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Detalles Bibliográficos
Autores principales:	Kantake, Masato, Ikeda, Naho, Nakaoka, Hirofumi, Ohkawa, Natsuki, Tanaka, Toshitaka, Miyabayashi, Kazuki, Shoji, Hiromichi, Shimizu, Toshiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364555/ https://www.ncbi.nlm.nih.gov/pubmed/32678007 http://dx.doi.org/10.1186/s13148-020-00901-w

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