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ADAM15 expression is increased in lung CD8(+) T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction

BACKGROUND: A disintegrin and metalloproteinase domain-15 (ADAM15) is expressed by activated leukocytes, and fibroblasts in vitro. Whether ADAM15 expression is increased in the lungs of COPD patients is not known. METHODS: ADAM15 gene expression and/or protein levels were measured in whole lung and...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoyun, Zhang, Duo, Higham, Andrew, Wolosianka, Sophie, Gai, Xiaoyan, Zhou, Lu, Petersen, Hans, Pinto-Plata, Victor, Divo, Miguel, Silverman, Edwin K., Celli, Bartolome, Singh, Dave, Sun, Yongchang, Owen, Caroline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364636/ https://www.ncbi.nlm.nih.gov/pubmed/32677970 http://dx.doi.org/10.1186/s12931-020-01446-5

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