Structural stability of the SARS-CoV-2 main protease: Can metal ions affect function?

We have investigated the structural stability of the SARS (Severe acute respiratory syndrome)-CoV-2 main protease monomer (Mpro). We quantified the spatial and angular changes in the structure using two independent analyses, one based on a spatial metrics (δ, ratio), the second on angular metrics. T...

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Detalles Bibliográficos
Autores principales: Kozak, John J., Gray, Harry B., Garza-López, Roberto A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365078/
https://www.ncbi.nlm.nih.gov/pubmed/32736274
http://dx.doi.org/10.1016/j.jinorgbio.2020.111179

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