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Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus
The intraparietal sulcus (IPS) is structurally and functionally heterogeneous. We performed a quantitative cyto-/myelo- and receptor architectonical analysis to provide a multimodal map of the macaque IPS. We identified 17 cortical areas, including novel areas PEipe, PEipi (external and internal sub...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365665/ https://www.ncbi.nlm.nih.gov/pubmed/32613942 http://dx.doi.org/10.7554/eLife.55979 |
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author | Niu, Meiqi Impieri, Daniele Rapan, Lucija Funck, Thomas Palomero-Gallagher, Nicola Zilles, Karl |
author_facet | Niu, Meiqi Impieri, Daniele Rapan, Lucija Funck, Thomas Palomero-Gallagher, Nicola Zilles, Karl |
author_sort | Niu, Meiqi |
collection | PubMed |
description | The intraparietal sulcus (IPS) is structurally and functionally heterogeneous. We performed a quantitative cyto-/myelo- and receptor architectonical analysis to provide a multimodal map of the macaque IPS. We identified 17 cortical areas, including novel areas PEipe, PEipi (external and internal subdivisions of PEip), and MIPd. Multivariate analyses of receptor densities resulted in a grouping of areas based on the degree of (dis)similarity of their receptor architecture: a cluster encompassing areas located in the posterior portion of the IPS and associated mainly with the processing of visual information, a cluster including areas found in the anterior portion of the IPS and involved in sensorimotor processing, and an ‘intermediate’ cluster of multimodal association areas. Thus, differences in cyto-/myelo- and receptor architecture segregate the cortical ribbon within the IPS, and receptor fingerprints provide novel insights into the relationship between the structural and functional segregation of this brain region in the macaque monkey. |
format | Online Article Text |
id | pubmed-7365665 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-73656652020-07-17 Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus Niu, Meiqi Impieri, Daniele Rapan, Lucija Funck, Thomas Palomero-Gallagher, Nicola Zilles, Karl eLife Neuroscience The intraparietal sulcus (IPS) is structurally and functionally heterogeneous. We performed a quantitative cyto-/myelo- and receptor architectonical analysis to provide a multimodal map of the macaque IPS. We identified 17 cortical areas, including novel areas PEipe, PEipi (external and internal subdivisions of PEip), and MIPd. Multivariate analyses of receptor densities resulted in a grouping of areas based on the degree of (dis)similarity of their receptor architecture: a cluster encompassing areas located in the posterior portion of the IPS and associated mainly with the processing of visual information, a cluster including areas found in the anterior portion of the IPS and involved in sensorimotor processing, and an ‘intermediate’ cluster of multimodal association areas. Thus, differences in cyto-/myelo- and receptor architecture segregate the cortical ribbon within the IPS, and receptor fingerprints provide novel insights into the relationship between the structural and functional segregation of this brain region in the macaque monkey. eLife Sciences Publications, Ltd 2020-07-02 /pmc/articles/PMC7365665/ /pubmed/32613942 http://dx.doi.org/10.7554/eLife.55979 Text en © 2020, Niu et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Niu, Meiqi Impieri, Daniele Rapan, Lucija Funck, Thomas Palomero-Gallagher, Nicola Zilles, Karl Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title | Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title_full | Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title_fullStr | Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title_full_unstemmed | Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title_short | Receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
title_sort | receptor-driven, multimodal mapping of cortical areas in the macaque monkey intraparietal sulcus |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365665/ https://www.ncbi.nlm.nih.gov/pubmed/32613942 http://dx.doi.org/10.7554/eLife.55979 |
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