Histone Methylation Inhibitor DZNep Ameliorated the Renal Ischemia-Reperfusion Injury via Inhibiting TIM-1 Mediated T Cell Activation

Renal ischemia-reperfusion injury (IRI) after renal transplantation often leads to the loss of kidney graft function. However, there is still a lack of efficient regimens to prevent or alleviate renal IRI. Our study focused on the renoprotective effect of 3-Deazaneplanocin A (DZNep), which is a hist...

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Detalles Bibliográficos
Autores principales: Li, Jiawei, Qiu, Yue, Li, Long, Wang, Jiyan, Cheuk, Yin Celeste, Sang, Ruirui, Jia, Yichen, Wang, Jina, Zhang, Yi, Rong, Ruiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365856/
https://www.ncbi.nlm.nih.gov/pubmed/32754604
http://dx.doi.org/10.3389/fmed.2020.00305

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