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Immune Thrombocytopenia in a Very Elderly Patient With Covid-19

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV...

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Autores principales: Hindilerden, Fehmi, Yonal-Hindilerden, Ipek, Sevtap, Senoglu, Kart-Yasar, Kadriye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365892/
https://www.ncbi.nlm.nih.gov/pubmed/32754609
http://dx.doi.org/10.3389/fmed.2020.00404
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author Hindilerden, Fehmi
Yonal-Hindilerden, Ipek
Sevtap, Senoglu
Kart-Yasar, Kadriye
author_facet Hindilerden, Fehmi
Yonal-Hindilerden, Ipek
Sevtap, Senoglu
Kart-Yasar, Kadriye
author_sort Hindilerden, Fehmi
collection PubMed
description Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus, rubella, and measles. Association with the new severe acute respiratory syndrome coronavirus, SARS-CoV-2 infection (Covid-19 infection) has been rarely reported. Here, we report the oldest case of ITP patient triggered by the novel coronavirus infection. He showed inadequate response to IVIG but responded to corticosteroids with no severe adverse events. Further studies are warranted to determine the optimal therapeutic strategies for ITP with the Covid-19 infection.
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spelling pubmed-73658922020-08-03 Immune Thrombocytopenia in a Very Elderly Patient With Covid-19 Hindilerden, Fehmi Yonal-Hindilerden, Ipek Sevtap, Senoglu Kart-Yasar, Kadriye Front Med (Lausanne) Medicine Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus, rubella, and measles. Association with the new severe acute respiratory syndrome coronavirus, SARS-CoV-2 infection (Covid-19 infection) has been rarely reported. Here, we report the oldest case of ITP patient triggered by the novel coronavirus infection. He showed inadequate response to IVIG but responded to corticosteroids with no severe adverse events. Further studies are warranted to determine the optimal therapeutic strategies for ITP with the Covid-19 infection. Frontiers Media S.A. 2020-07-10 /pmc/articles/PMC7365892/ /pubmed/32754609 http://dx.doi.org/10.3389/fmed.2020.00404 Text en Copyright © 2020 Hindilerden, Yonal-Hindilerden, Sevtap and Kart-Yasar. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Hindilerden, Fehmi
Yonal-Hindilerden, Ipek
Sevtap, Senoglu
Kart-Yasar, Kadriye
Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title_full Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title_fullStr Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title_full_unstemmed Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title_short Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
title_sort immune thrombocytopenia in a very elderly patient with covid-19
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365892/
https://www.ncbi.nlm.nih.gov/pubmed/32754609
http://dx.doi.org/10.3389/fmed.2020.00404
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