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Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy

PURPOSE: To present a small series of cases, in which single-fraction image-guided high-dose-rate (HDR) brachytherapy was provided as palliative treatment for inoperable head and neck cancer cases. MATERIAL AND METHODS: We used this technique to treat 3 patients with symptomatic head and neck cancer...

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Autores principales: Ota, Yoshiaki, Masui, Koji, Suzuki, Gen, Yamazaki, Hideya, Yamada, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366025/
https://www.ncbi.nlm.nih.gov/pubmed/32695200
http://dx.doi.org/10.5114/jcb.2020.96870
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author Ota, Yoshiaki
Masui, Koji
Suzuki, Gen
Yamazaki, Hideya
Yamada, Kei
author_facet Ota, Yoshiaki
Masui, Koji
Suzuki, Gen
Yamazaki, Hideya
Yamada, Kei
author_sort Ota, Yoshiaki
collection PubMed
description PURPOSE: To present a small series of cases, in which single-fraction image-guided high-dose-rate (HDR) brachytherapy was provided as palliative treatment for inoperable head and neck cancer cases. MATERIAL AND METHODS: We used this technique to treat 3 patients with symptomatic head and neck cancer (tongue cancer, gingival metastasis of osteosarcoma, and external auditory canal cancer), who were not eligible for a definitive treatment. The purpose of palliative brachytherapy in all 3 patients was the relief of symptoms such as difficulty in eating, talking, and hearing. All patients were treated with computed tomography (CT) image-guided interstitial HDR brachytherapy under local anesthesia in an outpatient setting, with a single dose of 10 Gy. RESULTS: Satisfactory palliative effects were achieved in all cases without serious side effects. The palliative effects were sustained in 2 patients until death, and 1 patient lived for 39 weeks before a relapse. CONCLUSIONS: Our palliative treatment technique appears to be safe, effective, and less invasive, and could be a treatment option for symptomatic patients with head and neck cancer.
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spelling pubmed-73660252020-07-20 Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy Ota, Yoshiaki Masui, Koji Suzuki, Gen Yamazaki, Hideya Yamada, Kei J Contemp Brachytherapy Case Report PURPOSE: To present a small series of cases, in which single-fraction image-guided high-dose-rate (HDR) brachytherapy was provided as palliative treatment for inoperable head and neck cancer cases. MATERIAL AND METHODS: We used this technique to treat 3 patients with symptomatic head and neck cancer (tongue cancer, gingival metastasis of osteosarcoma, and external auditory canal cancer), who were not eligible for a definitive treatment. The purpose of palliative brachytherapy in all 3 patients was the relief of symptoms such as difficulty in eating, talking, and hearing. All patients were treated with computed tomography (CT) image-guided interstitial HDR brachytherapy under local anesthesia in an outpatient setting, with a single dose of 10 Gy. RESULTS: Satisfactory palliative effects were achieved in all cases without serious side effects. The palliative effects were sustained in 2 patients until death, and 1 patient lived for 39 weeks before a relapse. CONCLUSIONS: Our palliative treatment technique appears to be safe, effective, and less invasive, and could be a treatment option for symptomatic patients with head and neck cancer. Termedia Publishing House 2020-06-30 2020-06 /pmc/articles/PMC7366025/ /pubmed/32695200 http://dx.doi.org/10.5114/jcb.2020.96870 Text en Copyright © 2020 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Case Report
Ota, Yoshiaki
Masui, Koji
Suzuki, Gen
Yamazaki, Hideya
Yamada, Kei
Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title_full Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title_fullStr Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title_full_unstemmed Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title_short Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
title_sort single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366025/
https://www.ncbi.nlm.nih.gov/pubmed/32695200
http://dx.doi.org/10.5114/jcb.2020.96870
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