Structure-based virtual screening of phytochemicals and repurposing of FDA approved antiviral drugs unravels lead molecules as potential inhibitors of coronavirus 3C-like protease enzyme

Coronaviruses are enveloped positive-strand RNA viruses belonging to family Coronaviridae and order Nidovirales which cause infections in birds and mammals. Among the human coronaviruses, highly pathogenic ones are Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and the Middle East Respirat...

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Detalles Bibliográficos
Autores principales: Bahadur Gurung, Arun, Ajmal Ali, Mohammad, Lee, Joongku, Abul Farah, Mohammad, Mashay Al-Anazi, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. on behalf of King Saud University. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366079/
https://www.ncbi.nlm.nih.gov/pubmed/32837113
http://dx.doi.org/10.1016/j.jksus.2020.07.007

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