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Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity

AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCo...

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Detalles Bibliográficos
Autores principales: Halvatsiotis, P., Kotanidou, A., Tzannis, K., Jahaj, E., Magira, E., Theodorakopoulou, M., Konstandopoulou, G., Gkeka, E., Pourzitaki, C., Kapravelos, N., Papoti, S., Sileli, M., Gogos, C., Velissaris, D., Markou, N., Stefanatou, E., Vlachogianni, G., Aimoniotou, E., Komnos, A., Zafeiridis, T., Koulouvaris, P., Armaganidis, A., Bamias, A., Dimopoulos, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366091/
https://www.ncbi.nlm.nih.gov/pubmed/32682810
http://dx.doi.org/10.1016/j.diabres.2020.108331
Descripción
Sumario:AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. RESULTS: The median age of the patients was 65.5 (IQR 56–73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5–11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3–9) vs. 9 (IQR 7–14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. CONCLUSIONS: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece.