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Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity

AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCo...

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Autores principales: Halvatsiotis, P., Kotanidou, A., Tzannis, K., Jahaj, E., Magira, E., Theodorakopoulou, M., Konstandopoulou, G., Gkeka, E., Pourzitaki, C., Kapravelos, N., Papoti, S., Sileli, M., Gogos, C., Velissaris, D., Markou, N., Stefanatou, E., Vlachogianni, G., Aimoniotou, E., Komnos, A., Zafeiridis, T., Koulouvaris, P., Armaganidis, A., Bamias, A., Dimopoulos, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366091/
https://www.ncbi.nlm.nih.gov/pubmed/32682810
http://dx.doi.org/10.1016/j.diabres.2020.108331
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author Halvatsiotis, P.
Kotanidou, A.
Tzannis, K.
Jahaj, E.
Magira, E.
Theodorakopoulou, M.
Konstandopoulou, G.
Gkeka, E.
Pourzitaki, C.
Kapravelos, N.
Papoti, S.
Sileli, M.
Gogos, C.
Velissaris, D.
Markou, N.
Stefanatou, E.
Vlachogianni, G.
Aimoniotou, E.
Komnos, A.
Zafeiridis, T.
Koulouvaris, P.
Armaganidis, A.
Bamias, A.
Dimopoulos, G.
author_facet Halvatsiotis, P.
Kotanidou, A.
Tzannis, K.
Jahaj, E.
Magira, E.
Theodorakopoulou, M.
Konstandopoulou, G.
Gkeka, E.
Pourzitaki, C.
Kapravelos, N.
Papoti, S.
Sileli, M.
Gogos, C.
Velissaris, D.
Markou, N.
Stefanatou, E.
Vlachogianni, G.
Aimoniotou, E.
Komnos, A.
Zafeiridis, T.
Koulouvaris, P.
Armaganidis, A.
Bamias, A.
Dimopoulos, G.
author_sort Halvatsiotis, P.
collection PubMed
description AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. RESULTS: The median age of the patients was 65.5 (IQR 56–73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5–11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3–9) vs. 9 (IQR 7–14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. CONCLUSIONS: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece.
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spelling pubmed-73660912020-07-17 Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity Halvatsiotis, P. Kotanidou, A. Tzannis, K. Jahaj, E. Magira, E. Theodorakopoulou, M. Konstandopoulou, G. Gkeka, E. Pourzitaki, C. Kapravelos, N. Papoti, S. Sileli, M. Gogos, C. Velissaris, D. Markou, N. Stefanatou, E. Vlachogianni, G. Aimoniotou, E. Komnos, A. Zafeiridis, T. Koulouvaris, P. Armaganidis, A. Bamias, A. Dimopoulos, G. Diabetes Res Clin Pract Article AIMS: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. RESULTS: The median age of the patients was 65.5 (IQR 56–73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5–11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3–9) vs. 9 (IQR 7–14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. CONCLUSIONS: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece. Elsevier B.V. 2020-08 2020-07-17 /pmc/articles/PMC7366091/ /pubmed/32682810 http://dx.doi.org/10.1016/j.diabres.2020.108331 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Halvatsiotis, P.
Kotanidou, A.
Tzannis, K.
Jahaj, E.
Magira, E.
Theodorakopoulou, M.
Konstandopoulou, G.
Gkeka, E.
Pourzitaki, C.
Kapravelos, N.
Papoti, S.
Sileli, M.
Gogos, C.
Velissaris, D.
Markou, N.
Stefanatou, E.
Vlachogianni, G.
Aimoniotou, E.
Komnos, A.
Zafeiridis, T.
Koulouvaris, P.
Armaganidis, A.
Bamias, A.
Dimopoulos, G.
Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title_full Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title_fullStr Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title_full_unstemmed Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title_short Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
title_sort demographic and clinical features of critically ill patients with covid-19 in greece: the burden of diabetes and obesity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366091/
https://www.ncbi.nlm.nih.gov/pubmed/32682810
http://dx.doi.org/10.1016/j.diabres.2020.108331
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