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Inactivating mutations in genes encoding for components of the BAF/PBAF complex and immune-checkpoint inhibitor outcome

Alterations of genes encoding subunits of the BAF/PBAF complexes are among the most frequent gene aberrations in human cancer. Such alterations have been shown to have an impact on tumor microenvironnement and on the capacity of tumors to respond to immune-checkpoint inhibitors (ICI). We analysed th...

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Detalles Bibliográficos
Autores principales: Courtet, Kevin, Laizet, Yec’han, Lucchesi, Carlo, Bessede, Alban, Italiano, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366303/
https://www.ncbi.nlm.nih.gov/pubmed/32695398
http://dx.doi.org/10.1186/s40364-020-00206-3