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Implementing a system for the real-time risk assessment of patients considered for intensive care

BACKGROUND: Delay in identifying deterioration in hospitalised patients is associated with delayed admission to an intensive care unit (ICU) and poor outcomes. For the HAVEN project (HICF ref.: HICF-R9–524), we have developed a mathematical model that identifies deterioration in hospitalised patient...

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Autores principales: Dahella, Simarjot S., Briggs, James S., Coombes, Paul, Farajidavar, Nazli, Meredith, Paul, Bonnici, Timothy, Darbyshire, Julie L., Watkinson, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366315/
https://www.ncbi.nlm.nih.gov/pubmed/32677936
http://dx.doi.org/10.1186/s12911-020-01176-0
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author Dahella, Simarjot S.
Briggs, James S.
Coombes, Paul
Farajidavar, Nazli
Meredith, Paul
Bonnici, Timothy
Darbyshire, Julie L.
Watkinson, Peter J.
author_facet Dahella, Simarjot S.
Briggs, James S.
Coombes, Paul
Farajidavar, Nazli
Meredith, Paul
Bonnici, Timothy
Darbyshire, Julie L.
Watkinson, Peter J.
author_sort Dahella, Simarjot S.
collection PubMed
description BACKGROUND: Delay in identifying deterioration in hospitalised patients is associated with delayed admission to an intensive care unit (ICU) and poor outcomes. For the HAVEN project (HICF ref.: HICF-R9–524), we have developed a mathematical model that identifies deterioration in hospitalised patients in real time and facilitates the intervention of an ICU outreach team. This paper describes the system that has been designed to implement the model. We have used innovative technologies such as Portable Format for Analytics (PFA) and Open Services Gateway initiative (OSGi) to define the predictive statistical model and implement the system respectively for greater configurability, reliability, and availability. RESULTS: The HAVEN system has been deployed as part of a research project in the Oxford University Hospitals NHS Foundation Trust. The system has so far processed > 164,000 vital signs observations and > 68,000 laboratory results for > 12,500 patients and the algorithm generated score is being evaluated to review patients who are under consideration for transfer to ICU. No clinical decisions are being made based on output from the system. The HAVEN score has been computed using a PFA model for all these patients. The intent is that this score will be displayed on a graphical user interface for clinician review and response. CONCLUSIONS: The system uses a configurable PFA model to compute the HAVEN score which makes the system easily upgradable in terms of enhancing systems’ predictive capability. Further system enhancements are planned to handle new data sources and additional management screens.
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spelling pubmed-73663152020-07-20 Implementing a system for the real-time risk assessment of patients considered for intensive care Dahella, Simarjot S. Briggs, James S. Coombes, Paul Farajidavar, Nazli Meredith, Paul Bonnici, Timothy Darbyshire, Julie L. Watkinson, Peter J. BMC Med Inform Decis Mak Research Article BACKGROUND: Delay in identifying deterioration in hospitalised patients is associated with delayed admission to an intensive care unit (ICU) and poor outcomes. For the HAVEN project (HICF ref.: HICF-R9–524), we have developed a mathematical model that identifies deterioration in hospitalised patients in real time and facilitates the intervention of an ICU outreach team. This paper describes the system that has been designed to implement the model. We have used innovative technologies such as Portable Format for Analytics (PFA) and Open Services Gateway initiative (OSGi) to define the predictive statistical model and implement the system respectively for greater configurability, reliability, and availability. RESULTS: The HAVEN system has been deployed as part of a research project in the Oxford University Hospitals NHS Foundation Trust. The system has so far processed > 164,000 vital signs observations and > 68,000 laboratory results for > 12,500 patients and the algorithm generated score is being evaluated to review patients who are under consideration for transfer to ICU. No clinical decisions are being made based on output from the system. The HAVEN score has been computed using a PFA model for all these patients. The intent is that this score will be displayed on a graphical user interface for clinician review and response. CONCLUSIONS: The system uses a configurable PFA model to compute the HAVEN score which makes the system easily upgradable in terms of enhancing systems’ predictive capability. Further system enhancements are planned to handle new data sources and additional management screens. BioMed Central 2020-07-16 /pmc/articles/PMC7366315/ /pubmed/32677936 http://dx.doi.org/10.1186/s12911-020-01176-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Dahella, Simarjot S.
Briggs, James S.
Coombes, Paul
Farajidavar, Nazli
Meredith, Paul
Bonnici, Timothy
Darbyshire, Julie L.
Watkinson, Peter J.
Implementing a system for the real-time risk assessment of patients considered for intensive care
title Implementing a system for the real-time risk assessment of patients considered for intensive care
title_full Implementing a system for the real-time risk assessment of patients considered for intensive care
title_fullStr Implementing a system for the real-time risk assessment of patients considered for intensive care
title_full_unstemmed Implementing a system for the real-time risk assessment of patients considered for intensive care
title_short Implementing a system for the real-time risk assessment of patients considered for intensive care
title_sort implementing a system for the real-time risk assessment of patients considered for intensive care
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366315/
https://www.ncbi.nlm.nih.gov/pubmed/32677936
http://dx.doi.org/10.1186/s12911-020-01176-0
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