The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during infection. The underlying mechanisms are unclear, but involve secretion of an unidentified mitogenic factor. Here, we use functional transposon-mutant screening in Bartonella henselae to identify such factor as a...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Kentaro, Shinzawa, Naoaki, Kawai, Akito, Suzuki, Masahiro, Kidoya, Hiroyasu, Takakura, Nobuyuki, Yamaguchi, Hisateru, Kameyama, Toshiki, Inagaki, Hidehito, Kurahashi, Hiroki, Horiguchi, Yasuhiko, Doi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366657/
https://www.ncbi.nlm.nih.gov/pubmed/32678094
http://dx.doi.org/10.1038/s41467-020-17391-2

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