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HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension (PAH) is overrepresented in People Living with Human Immunodeficiency Virus (PLWH). HIV protein gp120 plays a key role in the pathogenesis of HIV-PAH. Genetic changes in HIV gp120 determine viral interactions with chemokine receptors; specifically, HIV-X4 viruses inte...

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Detalles Bibliográficos
Autores principales:	Almodovar, Sharilyn, Wade, Brandy E., Porter, Kristi M., Smith, Justin M., Lopez-Astacio, Robert A., Bijli, Kaiser, Kang, Bum-Yong, Cribbs, Sushma K., Guidot, David M., Molehin, Deborah, McNair, Bryan K., Pumarejo-Gomez, Laura, Perez Hernandez, Jaritza, Salazar, Ethan A., Martinez, Edgar G., Huang, Laurence, Kessing, Cari F., Suarez-Martinez, Edu B., Pruitt, Kevin, Hsue, Priscilla Y., Tyor, William R., Flores, Sonia C., Sutliff, Roy L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366722/ https://www.ncbi.nlm.nih.gov/pubmed/32678115 http://dx.doi.org/10.1038/s41598-020-68060-9

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