Dual SMAD inhibition and Wnt inhibition enable efficient and reproducible differentiations of induced pluripotent stem cells into retinal ganglion cells

Glaucoma is a group of progressive optic neuropathies that share common biological and clinical characteristics including irreversible changes to the optic nerve and visual field loss caused by the death of retinal ganglion cells (RGCs). The loss of RGCs manifests as characteristic cupping or optic...

Descripción completa

Detalles Bibliográficos
Autores principales: Chavali, Venkata R. M., Haider, Naqi, Rathi, Sonika, Vrathasha, Vrathasha, Alapati, Teja, He, Jie, Gill, Kamaljot, Nikonov, Roman, Duong, Thu T., McDougald, Devin S., Nikonov, Sergei, O’Brien, Joan, Mills, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366935/
https://www.ncbi.nlm.nih.gov/pubmed/32678240
http://dx.doi.org/10.1038/s41598-020-68811-8

Ejemplares similares

Ejemplares similares