Cargando…

Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report

COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID...

Descripción completa

Detalles Bibliográficos
Autores principales: de Sousa, Gustavo Celeira, de Sousa, Thiago Celeira, Sakiyama, Marcelo Akira Kobayashi, da Silva, Jeanne Seabra Negrão Lima, de Sousa, Emanuel de Jesus Soares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367000/
https://www.ncbi.nlm.nih.gov/pubmed/33070890
http://dx.doi.org/10.1016/j.jocn.2020.07.034
_version_ 1783560335951659008
author de Sousa, Gustavo Celeira
de Sousa, Thiago Celeira
Sakiyama, Marcelo Akira Kobayashi
da Silva, Jeanne Seabra Negrão Lima
de Sousa, Emanuel de Jesus Soares
author_facet de Sousa, Gustavo Celeira
de Sousa, Thiago Celeira
Sakiyama, Marcelo Akira Kobayashi
da Silva, Jeanne Seabra Negrão Lima
de Sousa, Emanuel de Jesus Soares
author_sort de Sousa, Gustavo Celeira
collection PubMed
description COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management.
format Online
Article
Text
id pubmed-7367000
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-73670002020-07-20 Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report de Sousa, Gustavo Celeira de Sousa, Thiago Celeira Sakiyama, Marcelo Akira Kobayashi da Silva, Jeanne Seabra Negrão Lima de Sousa, Emanuel de Jesus Soares J Clin Neurosci Case Report COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management. Elsevier Ltd. 2020-09 2020-07-17 /pmc/articles/PMC7367000/ /pubmed/33070890 http://dx.doi.org/10.1016/j.jocn.2020.07.034 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
de Sousa, Gustavo Celeira
de Sousa, Thiago Celeira
Sakiyama, Marcelo Akira Kobayashi
da Silva, Jeanne Seabra Negrão Lima
de Sousa, Emanuel de Jesus Soares
Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title_full Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title_fullStr Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title_full_unstemmed Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title_short Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
title_sort vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (covid19) – case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367000/
https://www.ncbi.nlm.nih.gov/pubmed/33070890
http://dx.doi.org/10.1016/j.jocn.2020.07.034
work_keys_str_mv AT desousagustavoceleira vasculitisrelatedstrokeinyoungasapresentingfeatureofnovelcoronavirusdiseasecovid19casereport
AT desousathiagoceleira vasculitisrelatedstrokeinyoungasapresentingfeatureofnovelcoronavirusdiseasecovid19casereport
AT sakiyamamarceloakirakobayashi vasculitisrelatedstrokeinyoungasapresentingfeatureofnovelcoronavirusdiseasecovid19casereport
AT dasilvajeanneseabranegraolima vasculitisrelatedstrokeinyoungasapresentingfeatureofnovelcoronavirusdiseasecovid19casereport
AT desousaemanueldejesussoares vasculitisrelatedstrokeinyoungasapresentingfeatureofnovelcoronavirusdiseasecovid19casereport