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Substrate specificities of Escherichia coli ItaT that acetylates aminoacyl-tRNAs

Escherichia coli ItaT toxin reportedly acetylates the α-amino group of the aminoacyl-moiety of Ile-tRNA(Ile) specifically, using acetyl-CoA as an acetyl donor, thereby inhibiting protein synthesis. The mechanism of the substrate specificity of ItaT had remained elusive. Here, we present functional a...

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Detalles Bibliográficos
Autores principales:	Zhang, Chuqiao, Yashiro, Yuka, Sakaguchi, Yuriko, Suzuki, Tsutomu, Tomita, Kozo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367177/ https://www.ncbi.nlm.nih.gov/pubmed/32501503 http://dx.doi.org/10.1093/nar/gkaa487

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