Cargando…

Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription

Mono-ubiquitylation of histone H2B (H2Bub1) and phosphorylation of elongation factor Spt5 by cyclin-dependent kinase 9 (Cdk9) occur during transcription by RNA polymerase II (RNAPII), and are mutually dependent in fission yeast. It remained unclear whether Cdk9 and H2Bub1 cooperate to regulate the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Sansó, Miriam, Parua, Pabitra K, Pinto, Daniel, Svensson, J Peter, Pagé, Viviane, Bitton, Danny A, MacKinnon, Sarah, Garcia, Patricia, Hidalgo, Elena, Bähler, Jürg, Tanny, Jason C, Fisher, Robert P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367204/
https://www.ncbi.nlm.nih.gov/pubmed/32496538
http://dx.doi.org/10.1093/nar/gkaa474