Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway

BACKGROUND: The oral cavity is a complex environment in which periodontal tissue is constantly stimulated by external microorganisms and mechanical forces. Proper mechanical force helps maintain periodontal tissue homeostasis, and improper inflammatory response can break the balance. Periodontal lig...

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Detalles Bibliográficos
Autores principales: Lv, Pei-ying, Gao, Peng-fei, Tian, Guang-jie, Yang, Yan-yan, Mo, Fei-fei, Wang, Zi-hui, Sun, Lu, Kuang, Ming-jie, Wang, Yong-lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367226/
https://www.ncbi.nlm.nih.gov/pubmed/32680565
http://dx.doi.org/10.1186/s13287-020-01815-3

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