Negative feedback regulation by HuR controls TRIM21 expression and function in response to UV radiation

The E3 ubiquitin ligase TRIM21 plays a crucial role as a negative regulator of innate immune responses. Recent evidence has also indicated the involvement of TRIM21 in the genotoxic stress response and suppressing tumorigenesis. Our previous work has demonstrated a new function of TRIM21 in inhibiti...

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Detalles Bibliográficos
Autores principales: Guha, Abhishek, Nag, Sharanya, Ray, Partho Sarothi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367240/
https://www.ncbi.nlm.nih.gov/pubmed/32678213
http://dx.doi.org/10.1038/s41598-020-68646-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367240/
https://www.ncbi.nlm.nih.gov/pubmed/32678213
http://dx.doi.org/10.1038/s41598-020-68646-3

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