Combination of apolipoprotein-A-I/apolipoprotein-A-I binding protein and anti-VEGF treatment overcomes anti-VEGF resistance in choroidal neovascularization in mice

Many patients of choroidal neovascularization (CNV) are unresponsive to the current anti-VEGF treatment. The mechanisms for anti-VEGF resistance are poorly understood. We explore the unique property of the apolipoprotein A-I (apoA-I) binding protein (AIBP) that enhances cholesterol efflux from endot...

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Detalles Bibliográficos
Autores principales: Zhu, Lingping, Parker, Mackenzie, Enemchukwu, Nduka, Shen, Megan, Zhang, Guogang, Yan, Qing, Handa, James T., Fang, Longhou, Fu, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367303/
https://www.ncbi.nlm.nih.gov/pubmed/32678293
http://dx.doi.org/10.1038/s42003-020-1113-z

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