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Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma

Diffuse midline gliomas (DMGs) are aggressive pediatric brain tumors with dismal prognosis due to therapy-resistant tumor growth and invasion. We performed the first integrated histologic/genomic/proteomic analysis of 21 foci from three pontine DMG cases with supratentorial dissemination. Histone H3...

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Detalles Bibliográficos
Autores principales:	Georgescu, M.-M., Islam, M. Z., Li, Y., Circu, M. L., Traylor, J., Notarianni, C. M., Kline, C. N., Burns, D. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367358/ https://www.ncbi.nlm.nih.gov/pubmed/32680567 http://dx.doi.org/10.1186/s40478-020-00992-9

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