Cargando…

Identification of the key genes associated with chemotherapy sensitivity in ovarian cancer patients

BACKGROUND: Ovarian cancer (OC) is the deadliest gynecological cancer. The absence of biomarkers in early detection and chemotherapy resistance is a principal cause of treatment failure in OC. METHODS: In this study, next generation sequencing (NGS) was used to sequence the mRNA of 44 OC patients in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Hui, Zhang, Meiqin, Ma, Shuang, Yang, Wenting, Xie, Suhong, Wang, Yanchun, Liu, Yixuan, Kai, Jinyan, Ma, Qian, Lu, Renquan, Guo, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367617/ https://www.ncbi.nlm.nih.gov/pubmed/32441484 http://dx.doi.org/10.1002/cam4.3122

Ejemplares similares

Elevated serum HER‐2 predicts poor prognosis in breast cancer and is correlated to ADAM10 expression
por: Zheng, Hui, et al.
Publicado: (2019)

MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3–phospho-BAD pathway
por: Guan, Xiaolin, et al.
Publicado: (2022)

Inhibition of MCM2 enhances the sensitivity of ovarian cancer cell to carboplatin
por: Deng, Minjie, et al.
Publicado: (2019)

VHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4-mediated metabolic stress via HIF-1α/HO-1 pathway
por: Tong, Ying, et al.
Publicado: (2021)

TTK is a potential therapeutic target for cisplatin-resistant ovarian cancer
por: Liu, Yixuan, et al.
Publicado: (2021)

GSG2 Promotes Development and Predicts Poor Prognosis of Ovarian Cancer
por: Huang, Yan, et al.
Publicado: (2021)

TPX2 promotes ovarian tumorigenesis by interacting with Lamin A/C and affecting its stability
por: Meng, Xin, et al.
Publicado: (2023)

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
por: Diaz Osterman, Carlos J, et al.
Publicado: (2019)

MUS81 Participates in the Progression of Serous Ovarian Cancer Associated With Dysfunctional DNA Repair System
por: Lu, Renquan, et al.
Publicado: (2019)

Hyperbaric oxygen therapy sensitizes nimustine treatment for glioma in mice
por: Lu, Zhaohui, et al.
Publicado: (2016)

Identification of a six‐gene signature with prognostic value for patients with endometrial carcinoma
por: Wang, Yizi, et al.
Publicado: (2018)

IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis
por: Zheng, Hui, et al.
Publicado: (2023)

Identification of key lncRNAs in the tumorigenesis of intraductal pancreatic mucinous neoplasm by coexpression network analysis
por: Ding, Jun, et al.
Publicado: (2020)

Lipin‐1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy
por: Fan, Xueyu, et al.
Publicado: (2018)

Functional transcriptomic annotation and protein–protein interaction analysis identify EZH2 and UBE2C as key upregulated proteins in ovarian cancer
por: Martínez‐Canales, Sandra, et al.
Publicado: (2018)

Arginase 1 is a key driver of immune suppression in pancreatic cancer
por: Menjivar, Rosa E, et al.
Publicado: (2023)

Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells
por: Vanden Heuvel, John P, et al.
Publicado: (2018)

Poly-amino acids coated gold nanorod and doxorubicin for synergistic photodynamic therapy and chemotherapy in ovarian cancer cells
por: Liu, JinYing, et al.
Publicado: (2019)

LncRNA MALAT1 accelerates non‐small cell lung cancer progression via regulating miR‐185‐5p/MDM4 axis
por: Wang, Dan, et al.
Publicado: (2020)

Serology-Based Model for Personalized Epithelial Ovarian Cancer Risk Evaluation
por: Yan, Tianqing, et al.
Publicado: (2022)

Up-regulation of GSTT1 in serous ovarian cancer associated with resistance to TAXOL / carboplatin
por: Zhang, Jing, et al.
Publicado: (2021)

PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation
por: Mao, Yize, et al.
Publicado: (2018)

Downregulation of AGR2, p21, and cyclin D and alterations in p53 function were associated with tumor progression and chemotherapy resistance in epithelial ovarian carcinoma
por: Alves, Mariana Rezende, et al.
Publicado: (2018)

MiR‐335‐5p restores cisplatin sensitivity in ovarian cancer cells through targeting BCL2L2
por: Liu, Ruonan, et al.
Publicado: (2018)

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor
por: Franklin, Miriam, et al.
Publicado: (2018)

lncRNA ABHD11‐AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2
por: Zeng, Xiang‐Yang, et al.
Publicado: (2019)

Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas
por: Zhou, Ding, et al.
Publicado: (2021)

ONC201 induces the unfolded protein response (UPR) in high‐ and low‐grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity
por: Rumman, Marufa, et al.
Publicado: (2021)

PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors
por: Shi, Kaixuan, et al.
Publicado: (2019)

Identification of aberrantly methylated differentially expressed genes and associated pathways in endometrial cancer using integrated bioinformatic analysis
por: Liu, JinHui, et al.
Publicado: (2020)

Identification of a 6‐lncRNA prognostic signature based on microarray re‐annotation in gastric cancer
por: Ma, Bin, et al.
Publicado: (2019)

Clinical observations of bone marrow transfusion for promoting bone marrow reconstruction after chemotherapy for AIDS-related lymphoma
por: Liu, Yixuan, et al.
Publicado: (2021)

Long noncoding RNA NORAD is upregulated in epithelial ovarian cancer and its downregulation suppressed cancer cell functions by competing with miR‐155‐5p
por: Tong, Lingling, et al.
Publicado: (2019)

An integrated analysis reveals the oncogenic function of lncRNA LINC00511 in human ovarian cancer
por: Wang, Jing, et al.
Publicado: (2019)

Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V)1.5‐mediated EMT and FAK/Paxillin signaling pathway
por: Liu, Chang, et al.
Publicado: (2020)

Long noncoding RNA RP11‐547D24.1 regulates proliferation and migration in papillary thyroid carcinoma: Identification and validation of a novel long noncoding RNA through integrated analysis of TCGA database
por: Guo, Kai, et al.
Publicado: (2019)

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma
por: Fianco, Giulia, et al.
Publicado: (2017)

Human leukocyte antigen-E alleles and expression in patients with serous ovarian cancer
por: Zheng, Hui, et al.
Publicado: (2015)

First‐line therapy of bevacizumab plus chemotherapy versus cetuximab plus chemotherapy for metastatic colorectal cancer patients with mucinous adenocarcinoma or mucinous component
por: Zhou, Yu‐Wen, et al.
Publicado: (2021)

Significance of lymphovascular space invasion in epithelial ovarian cancer
por: Matsuo, Koji, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_lffht6igtkrcsu3vaj2dqfaud4