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Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?

Osteosarcoma is an aggressive bone tumor of the pediatric age. It is therefore important to improve conventional therapies (chemotherapy and surgery). Anticancer drugs often cause osteoporosis due to a misbalance of RANK/RANK-L/OPG pathway. Denosumab is a monoclonal antibody with high affinity and s...

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Detalles Bibliográficos
Autores principales:	Punzo, Francesca, Tortora, Chiara, Argenziano, Maura, Pinto, Daniela Di, Pota, Elvira, Martino, Martina Di, Paola, Alessandra Di, Rossi, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367655/ https://www.ncbi.nlm.nih.gov/pubmed/32733647 http://dx.doi.org/10.18632/oncotarget.27669

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