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Reconstitution reveals two paths of force transmission through the kinetochore

Partitioning duplicated chromosomes equally between daughter cells is a microtubule-mediated process essential to eukaryotic life. A multi-protein machine, the kinetochore, drives chromosome segregation by coupling the chromosomes to dynamic microtubule tips, even as the tips grow and shrink through...

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Detalles Bibliográficos
Autores principales:	Hamilton, Grace E, Helgeson, Luke A, Noland, Cameron L, Asbury, Charles L, Dimitrova, Yoana N, Davis, Trisha N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367685/ https://www.ncbi.nlm.nih.gov/pubmed/32406818 http://dx.doi.org/10.7554/eLife.56582

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