GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This study describes the first animal model lacking the enzyme glutamic acid decarboxy...

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Detalles Bibliográficos
Autores principales: Mahootchi, Elaheh, Cannon Homaei, Selina, Kleppe, Rune, Winge, Ingeborg, Hegvik, Tor-Arne, Megias-Perez, Roberto, Totland, Christian, Mogavero, Floriana, Baumann, Anne, Glennon, Jeffrey Colm, Miletic, Hrvoje, Kursula, Petri, Haavik, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367687/
https://www.ncbi.nlm.nih.gov/pubmed/32733999
http://dx.doi.org/10.1126/sciadv.abb3713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367687/
https://www.ncbi.nlm.nih.gov/pubmed/32733999
http://dx.doi.org/10.1126/sciadv.abb3713

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