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GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production
Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This study describes the first animal model lacking the enzyme glutamic acid decarboxy...
Autores principales: | Mahootchi, Elaheh, Cannon Homaei, Selina, Kleppe, Rune, Winge, Ingeborg, Hegvik, Tor-Arne, Megias-Perez, Roberto, Totland, Christian, Mogavero, Floriana, Baumann, Anne, Glennon, Jeffrey Colm, Miletic, Hrvoje, Kursula, Petri, Haavik, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367687/ https://www.ncbi.nlm.nih.gov/pubmed/32733999 http://dx.doi.org/10.1126/sciadv.abb3713 |
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