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Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
The majority of women with recurrent ovarian cancer (OvCa) develop malignant ascites with volumes that can reach > 2 L. The resulting elevation in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes striking changes in the loading environment in the peritone...
Autores principales: | Asem, Marwa, Young, Allison, Oyama, Carlysa, ClaureDeLaZerda, Alejandro, Liu, Yueying, Ravosa, Matthew. J., Gupta, Vijayalaxmi, Jewell, Andrea, Khabele, Dineo, Stack, M. Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367827/ https://www.ncbi.nlm.nih.gov/pubmed/32681052 http://dx.doi.org/10.1038/s41598-020-68639-2 |
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