Sirtuin-1 expression and activity is diminished in aged liver grafts

The cellular mechanisms underlying impaired function of aged liver grafts have not been fully elucidated, but mitochondrial dysfunction appears to be contributory. Sirtuin1 has been identified as a key mediator of mitochondrial recovery following ischemia–reperfusion injury. The purpose of this stud...

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Detalles Bibliográficos
Autores principales: Scheuermann, Uwe, Seyferth, Elisabeth R., Abraham, Nader, Kesseli, Samuel J., Halpern, Samantha E., Zhu, Minghua, Song, Mingqing, Hartwig, Matthew G., Parker, William, Kwun, Jean, Cherry, Anne D., Lee, Jaewoo, Barbas, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367862/
https://www.ncbi.nlm.nih.gov/pubmed/32681076
http://dx.doi.org/10.1038/s41598-020-68314-6

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